A poisoned reputation

A collusion mitigation scheme for reputation systems

Reputation management systems are in wide-spread use to regulate collaborations in cooperative systems. Collusion is one of the most destructive malicious behaviors in which colluders seek to affect a reputation management system in an unfair manner. Many reputation systems are vulnerable to collusion, and some model-specific mitigation methods are proposed to combat collusion. Detection of col...

Treatment efficacy in a soman poisoned guinea

Pseudokinase drug intervention: a potentially poisoned chalice.

Pseudokinases, the catalytically impaired component of the kinome, have recently been found to share more properties with active kinases than previously thought. In many pseudokinases, ATP binding and even some activity is preserved, highlighting these proteins as potential drug targets. In both active kinases and pseudokinases, binding of ATP or drugs in the nucleotide-binding pocket can stabi...

GGRA: a grouped gossip-based reputation aggregation algorithm

An important issue in P2P networks is the existence of malicious nodes that decreases the performance of such networks. Reputation system in which nodes are ranked based on their behavior, is one of the proposed solutions to detect and isolate malicious (low ranked) nodes. Gossip Trust is an interesting previously proposed algorithm for reputation aggregation in P2P networks based on t...

The Poisoned Pediatric Patient.

1. Understand the epidemiology of pediatric poisonings and explain how developmental milestones influence behavior that may lead to a poisoning exposure. 2. Perform a focused toxicologic physical examination and describe the various toxidromes. 3. Explain the primary acid-base disturbance in salicylate toxicity. 4. Determine which patient requires treatment after acute acetaminophen ingestion. ...